Introduction
In a rapidly expanding CBD market filled with countless brands and products, PlusCBD by CV Sciences has earned a reputation as one of the most reliable and scientifically backed CBD brands available today. Known for its commitment to quality, safety, and transparency, PlusCBD is a favorite among both wellness enthusiasts and healthcare professionals.
Whether you’re seeking relief from anxiety, pain, inflammation, or looking to support your general wellness, PlusCBD offers premium CBD products that are rigorously tested and formulated to deliver results. In this comprehensive review, we’ll cover everything you need to know—from sourcing and extraction methods to customer feedback and real-world benefits.
About the Brand: Who is PlusCBD?

PlusCBD™ is the flagship consumer brand of CV Sciences, Inc., a publicly traded life science company (OTCQB: CVSI) dedicated to advancing hemp-based science and natural wellness. Headquartered in San Diego, CV Sciences has a long-standing reputation for integrity and transparency in the health supplement industry.
Unlike many CBD startups, PlusCBD is science-driven—with research-backed formulations, ongoing clinical studies, and a safety record that meets or exceeds industry standards.
🌿 Mission Statement:
“To improve well-being through nature and science, delivering the highest quality hemp-derived CBD products on the market.”
What Makes PlusCBD Stand Out?
1. EU-Certified Hemp
PlusCBD sources its hemp from sustainably grown farms in the Netherlands, which adhere to rigorous agricultural standards. This ensures a clean, potent, and phytocannabinoid-rich crop.
2. Advanced CO₂ Extraction
Using supercritical CO₂ extraction, PlusCBD preserves the full spectrum of cannabinoids, terpenes, and plant nutrients without using harsh solvents or chemicals.
3. Full-Traceability & QR Codes
Every product comes with a QR code that links to lab reports, allowing you to verify:
- CBD potency
- THC content
- Heavy metals
- Pesticide residue
- Microbial purity
4. GRAS Status and Clinical Research
PlusCBD was the first CBD brand to achieve self-affirmed GRAS (Generally Recognized As Safe) status, and has participated in peer-reviewed clinical trials, demonstrating safety and efficacy.
5. cGMP-Certified Facilities
All manufacturing takes place in current Good Manufacturing Practice (cGMP)-certified facilities, ensuring consistency and cleanliness from seed to shelf.
PlusCBD Product Catalog (Detailed)

🔹 1. CBD Oil Drops (Full-Spectrum & THC-Free)
Best for: Daily wellness, stress, sleep, inflammation
- Potencies: 250mg, 750mg, 1500mg
- Flavors: Peppermint, Goji Blueberry, Unflavored
- Formulas: Full-spectrum (trace THC) or THC-free
- Features: Olive oil base, naturally flavored, vegan
🔹 2. CBD Gummies
Best for: Beginners, mood support, sleep
- Potency: 10mg CBD per gummy
- Options: Calm (with L-theanine), Sleep (with melatonin), regular
- Flavors: Cherry Mango, Citrus Punch
- Vegan, gluten-free, no artificial sweeteners
🔹 3. CBD Softgels & Capsules
Best for: Consistent daily dosing
- Potency: 15mg or 50mg CBD per capsule
- Formula: Full-spectrum with extra virgin olive oil
- Benefits: Supports stress response, inflammation, immune function
🔹 4. CBD Topicals
Best for: Joint pain, soreness, skincare
- Products: Muscle Balm, Pain Relief Cream, Roll-On, Skin Serum
- Active ingredients: Menthol, camphor, cocoa butter, shea
- Fast-acting, non-greasy, dermatologist-tested
🔹 5. CBD Oral Sprays
Best for: On-the-go microdosing
- Potency: 100mg–500mg per bottle
- Flavor: Peppermint
- Easy-to-use pump spray for sublingual delivery
Health Benefits of PlusCBD Products
While the FDA does not allow CBD companies to make medical claims, anecdotal reports and preliminary studies suggest that PlusCBD products may support:

- ✅ Stress & Anxiety Relief
Many users report feeling calmer and more balanced throughout the day. - ✅ Improved Sleep Quality
Especially with the Sleep Gummies that combine CBD and melatonin. - ✅ Pain and Inflammation Management
The topical line is frequently praised for easing sore muscles and chronic joint pain. - ✅ Mood Support
L-theanine and CBD work together in the “Calm” formula for emotional balance. - ✅ Focus and Clarity
Users say regular CBD use supports clearer thinking and focus without drowsiness.
PlusCBD Customer Reviews and Reputation
PlusCBD reviews are overwhelmingly positive, with thousands of verified customers praising:
- Quick and reliable shipping
- Noticeable effects within days
- High-quality packaging
- Customer support that’s helpful and responsive
- Clean taste and ease of use
💬 “I’ve tried over 10 different brands, and PlusCBD is the most consistent. I sleep better, feel less stressed, and my back pain is more manageable.”
– Verified customer review
Pricing & Where to Buy
- Pricing Range: $19.99 – $99.99 depending on product and potency
- Shipping: Free shipping on orders over $45
- Loyalty Program: Earn points and rewards on every purchase
- Where to Buy:
- Official PlusCBD Website (best for discounts and bundles)
- Amazon (limited selection)
- Select health food stores and pharmacies
Pros and Cons of PlusCBD
Pros | Cons |
---|---|
Trusted, long-standing brand | Slightly more expensive than generic CBD |
Full transparency and QR codes | Full-spectrum products contain trace THC |
Wide product selection | Gummies limited to 10mg strength |
Scientifically supported formulations | Some products only available online |
Vegan and clean ingredients | Mild flavor may not appeal to all |
Final Thoughts: Is PlusCBD Worth It?
Yes—PlusCBD is absolutely worth trying, especially if you’re looking for a scientifically validated, clean-label, and well-trusted CBD brand. With a solid safety record, innovative formulas, and transparent practices, PlusCBD remains one of the best CBD brands of 2025.
Whether you’re new to cannabidiol or looking to upgrade your current regimen, PlusCBD offers wellness products that deliver on their promise—relief, balance, and better living.